Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Moderately Good
Based on 29 Reviews
7.9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Selenium (elemental) (from 20 mg L-Selenomethionine)
100 mcg
182%

Top Medical Research Studies

8
Selenium effects on chronic fatigue
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
Read More
8
Selenium nanoparticles for chronic fatigue
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.

While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
Read More
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
Read More

Most Useful Reviews

9
Great overall health
4 people found this helpful
After two months of selenium, I feel fantastic. My skin glows, my mood has improved, and my fatigue has dissipated. I believe this is one of the best products for overall health maintenance, and the tablets are easy to swallow.
Read More
7.5
Thyroid support
4 people found this helpful
This product effectively alleviates my fatigue since it aids in iodine absorption, ensuring my thyroid gland functions optimally. I recommend taking it before lunch.
Read More
9
Fatigue vanished
2 people found this helpful
I was delighted with the selenium dietary supplement. The ingredients are high-quality, and the packaging is user-friendly. I take it daily, and I’ve noticed that my mood has improved, and my fatigue has dissipated. I've recently had thyroid hormone tests, and everything is normal! I recommend it wholeheartedly!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
  • All Researches
8
Selenium nanoparticles for chronic fatigue
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.

While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
Read More
8
Selenium effects on chronic fatigue
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
Read More
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 29 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Great overall health
4 people found this helpful
After two months of selenium, I feel fantastic. My skin glows, my mood has improved, and my fatigue has dissipated. I believe this is one of the best products for overall health maintenance, and the tablets are easy to swallow.
Read More
7.5
Thyroid support
4 people found this helpful
This product effectively alleviates my fatigue since it aids in iodine absorption, ensuring my thyroid gland functions optimally. I recommend taking it before lunch.
Read More
9
Fatigue vanished
2 people found this helpful
I was delighted with the selenium dietary supplement. The ingredients are high-quality, and the packaging is user-friendly. I take it daily, and I’ve noticed that my mood has improved, and my fatigue has dissipated. I've recently had thyroid hormone tests, and everything is normal! I recommend it wholeheartedly!
Read More
9
Chronic fatigue relief
1 people found this helpful
An effective remedy for overall health, immunity, and compensating for selenium deficiency. The quality and composition are commendable without complaints. The dosage is higher than similar products, offering excellent efficiency and absorption. It alleviates chronic fatigue, benefits skin and hair, and is suitable for families of varying ages. The tablets are small and easy to swallow, and the packaging is convenient and airtight.
Read More
9
Improvements seen
1 people found this helpful
I truly enjoyed the selenium supplement. Its high-quality ingredients and convenient packaging were noteworthy. I take it once daily, and it has a neutral taste. This supplement compensates for deficiencies and works excellently alongside iodine. I've noticed improved mood and a reduction in fatigue, and my recent thyroid hormone tests were normal. I'm pleased to recommend it!
Read More

Frequently Asked Questions

7.5
Significant energy boost
98 people found this helpful
I've been using the product for two weeks, and I've noticed a significant improvement in my energy levels. I would recommend this to anyone suffering from fatigue or general exhaustion. Life is long enough, and stress can be debilitating, affecting both physical and mental health.
9
Great overall health
4 people found this helpful
After two months of selenium, I feel fantastic. My skin glows, my mood has improved, and my fatigue has dissipated. I believe this is one of the best products for overall health maintenance, and the tablets are easy to swallow.
7.5
Increased energy levels
525 people found this helpful
I started taking Selenium to address issues like dull and brittle hair, gastrointestinal problems, fatigue, and to boost my immune system. My dermatologist suggested combining it with Zinc. The results were quite remarkable! I felt a surge of energy and woke up much more vigorously. In addition, my nails improved dramatically with rapid growth, and I experienced clearer skin. I highly recommend this supplement as its benefits are extensive; however, results may vary per individual.
7.5
Vital deficiency addressed
2 people found this helpful
A deficiency of selenium could present symptoms like muscle weakness, chronic fatigue, and weakened immunity. Living in an ecologically unfavourable area, I bought selenium upon my homeopath's advice. After a course, my condition improved significantly.
9
Fatigue reduction
I’ve noticed that the fatigue disappears after taking this supplement.
7.5
Improved energy levels
1 people found this helpful
Since taking the supplement, my energy levels and mental clarity have significantly improved. I feel alert and focused throughout the day, accomplishing more without the weariness. It's easy to take and has not caused any negative side effects.
9
Improved energy
1 people found this helpful
Since starting this supplement, my overall well-being has improved swiftly. The fatigue has decreased remarkably, especially when combined with L-tyrosine. Drowsiness and weakness have subsided, leaving me with energy and clarity. I truly appreciate this combination.
6
Reliable supplement
2 people found this helpful
I consistently purchase from this trustworthy brand, which offers excellent hermetic packaging and a convenient cap. I bought selenium for hair shedding, and it has numerous benefits. It has helped my immune system and reduced my fatigue, making it easier to combine with biotin.
9
Long-term use
This is the best antioxidant for me; I intend to take it for life. Taking one pill twice daily has made a noticeable difference. My fatigue has been considerably reduced.
7.5
Eye relief
1 people found this helpful
This supplement is fantastic for my thyroid eye disease. It has alleviated symptoms like fatigue and watering in my eyes. I’ve noticed improvement since taking these daily; missing doses makes symptoms return, indicating a possible selenium deficiency.
9
Fatigue relief
1 people found this helpful
Selenium has significantly helped me; my fatigue has vanished and my whole body feels rejuvenated. It turns out I was deficient in this vitamin. Thank you!
8
Selenium effects on chronic fatigue
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
8
Selenium nanoparticles for chronic fatigue
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.

While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.

References

  1. Wang J, Wang X, Xiu W, Li C, Yu S, et al. Ultrasound-assisted preparation of sweet corn cob polysaccharide selenium nanoparticles alleviates symptoms of chronic fatigue syndrome. Food Funct. 2025;16:133. 10.1039/d4fo04195j
  2. Castro-Marrero J, Domingo JC, Cordobilla B, Ferrer R, Giralt M, et al. Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?. Antioxid Redox Signal. 2022;36:729. 10.1089/ars.2022.0018
  3. Shao C, Song J, Zhao S, Jiang H, Wang B, et al. Therapeutic Effect and Metabolic Mechanism of A Selenium-Polysaccharide from Green Tea on Chronic Fatigue Syndrome. Polymers (Basel). 2018;10. 10.3390/polym10111269
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