We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
Read More
8
Selenium nanoparticles for chronic fatigue
Ultrasound-assisted preparation of sweet corn cob polysaccharide selenium nanoparticles alleviates symptoms of chronic fatigue syndrome.
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
Read More
7
CoQ10 and selenium may benefit ME/CFS
Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
Read More
Most Useful Reviews
9
Great overall health
4 people found this helpful
After two months of selenium, I feel fantastic. My skin glows, my mood has improved, and my fatigue has dissipated. I believe this is one of the best products for overall health maintenance, and the tablets are easy to swallow.
Read More
7.5
Thyroid support
4 people found this helpful
This product effectively alleviates my fatigue since it aids in iodine absorption, ensuring my thyroid gland functions optimally. I recommend taking it before lunch.
Read More
9
Fatigue vanished
2 people found this helpful
I was delighted with the selenium dietary supplement. The ingredients are high-quality, and the packaging is user-friendly. I take it daily, and I’ve noticed that my mood has improved, and my fatigue has dissipated. I've recently had thyroid hormone tests, and everything is normal! I recommend it wholeheartedly!
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
Read More
8
Selenium effects on chronic fatigue
Therapeutic Effect and Metabolic Mechanism of A Selenium-Polysaccharide from Green Tea on Chronic Fatigue Syndrome.
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
Read More
7
CoQ10 and selenium may benefit ME/CFS
Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 29 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
9
Great overall health
4 people found this helpful
After two months of selenium, I feel fantastic. My skin glows, my mood has improved, and my fatigue has dissipated. I believe this is one of the best products for overall health maintenance, and the tablets are easy to swallow.
Read More
7.5
Thyroid support
4 people found this helpful
This product effectively alleviates my fatigue since it aids in iodine absorption, ensuring my thyroid gland functions optimally. I recommend taking it before lunch.
Read More
9
Fatigue vanished
2 people found this helpful
I was delighted with the selenium dietary supplement. The ingredients are high-quality, and the packaging is user-friendly. I take it daily, and I’ve noticed that my mood has improved, and my fatigue has dissipated. I've recently had thyroid hormone tests, and everything is normal! I recommend it wholeheartedly!
Read More
9
Chronic fatigue relief
1 people found this helpful
An effective remedy for overall health, immunity, and compensating for selenium deficiency. The quality and composition are commendable without complaints. The dosage is higher than similar products, offering excellent efficiency and absorption. It alleviates chronic fatigue, benefits skin and hair, and is suitable for families of varying ages. The tablets are small and easy to swallow, and the packaging is convenient and airtight.
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9
Improvements seen
1 people found this helpful
I truly enjoyed the selenium supplement. Its high-quality ingredients and convenient packaging were noteworthy. I take it once daily, and it has a neutral taste. This supplement compensates for deficiencies and works excellently alongside iodine. I've noticed improved mood and a reduction in fatigue, and my recent thyroid hormone tests were normal. I'm pleased to recommend it!
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Selenium is a powerful and widely used open-source tool designed for automating web applications for testing purposes. It enables developers and testers to write code in various programming languages such as Java, Python, C#, and Ruby to simulate user interactions with a web browser. Selenium's flexibility allows users to create complex test scenarios that mimic real-world user behaviors, making it an essential tool for ensuring web application functionality and performance.
In addition to its core functionalities, Selenium consists of several components, including Selenium WebDriver for automating browsers, Selenium Grid for running tests across multiple machines and environments in parallel, and Selenium IDE for record-and-playback test creation. Its compatibility with multiple browser types—such as Chrome, Firefox, Safari, and Edge—makes it a versatile choice for automated testing, catering to a wide range of projects and team needs. For anyone involved in web development or quality assurance, understanding and utilizing Selenium can significantly improve testing efficiency and reliability.
Based on user reviews, the time it typically takes to see results from taking selenium supplements for Chronic Fatigue Syndrome can vary. Several users have reported feeling significant improvements within a few weeks to a couple of months. For instance, one user mentioned that after just two weeks of use, they noticed a marked increase in energy levels and a reduction in fatigue Read Review. Another user experienced a transformative effect after two months, stating they felt fantastic with diminished fatigue and improved mood Read Review.
However, it's important to note that results can be highly individual. Some users have expressed that while they began to feel some benefits relatively quickly, the full effects may take longer to manifest, depending on personal health circumstances and consistency of use Read Review, Read Review. Overall, patience and adherence to the recommended dosage seems essential for the best outcomes.
While there is emerging research on the potential benefits of specific supplements, such as selenium and Coenzyme Q10, for individuals with Chronic Fatigue Syndrome (CFS), the results are mixed. A study investigating the effects of selenium-polysaccharides from green tea found improvements in certain metabolic markers in a rat model, indicating a possible positive response related to fatigue. However, the effectiveness of this treatment for managing actual CFS symptoms in humans remains unconfirmed ([3]). Similarly, a study on combining Coenzyme Q10 and selenium showed some benefits in reducing fatigue severity and enhancing quality of life for CFS patients, though these were accompanied by no significant improvements in sleep disturbances or other biomarkers ([2]).
On the other hand, research regarding sweet corn cob selenium nanoparticles revealed that, despite their promise in enhancing energy production and gut microbiota, they did not show significant improvements in clinical symptoms of CFS ([1]). In summary, while certain supplements may have potential mechanisms that could theoretically assist with CFS symptoms, the scientific backing is not robust enough to definitively recommend them at this time, and further studies are necessary to establish their efficacy in managing CFS.
Many users have reported considerable improvements in their fatigue levels and overall mood after taking selenium supplements. For example, one user stated that they felt "fantastic" after two months, with diminished fatigue and improved skin and mood Read Review. Additionally, another user mentioned that their fatigue disappeared entirely with regular use of the supplement Read Review. Many users have highlighted that the improvements in energy levels often follow after a few days to weeks of consistent intake, suggesting that the benefits might accumulate over time.
Anecdotal experiences also align with enhanced mental clarity and vitality, with several users noting an uplift in their mood and daily functioning Read Review, Read Review. While one participant mentioned they experienced an increase in overall energy after combining selenium with L-tyrosine, emphasizing the importance of individual variations in response to supplementation Read Review. It’s essential to recognize that results can vary significantly between individuals, depending on factors such as specific health conditions and existing deficiencies, necessitating a tailored approach to supplementation.
Based on user reviews, the combination of selenium with other supplements appears to be beneficial for managing Chronic Fatigue Syndrome. One user reported remarkable improvements in energy levels and overall vitality after combining selenium with L-tyrosine, stating that fatigue, drowsiness, and weakness subsided significantly, leaving them energized and clear-headed Read Review. Additionally, a user who combined selenium with zinc found that it helped combat various issues, including fatigue, resulting in a boost of energy and improved skin and nail health Read Review.
Moreover, another review highlighted the effective pairing of selenium with biotin for addressing fatigue while also supporting hair health Read Review. These experiences suggest that users often explore synergistic effects between selenium and other micronutrients, advocating for a tailored approach to supplementation geared toward individual health needs. Overall, such combinations seem to enhance the overall effectiveness of addressing symptoms associated with Chronic Fatigue Syndrome.
Based on user reviews, Selenium supplements appear to be beneficial for individuals experiencing Chronic Fatigue Syndrome. Users report varying dosages, with many referencing a standard intake of 100 micrograms per day. For instance, one user noted that taking one pill twice daily resulted in a noticeable reduction in fatigue, leading them to describe it as the best antioxidant for their health Read Review. Others emphasize the importance of consistency in taking Selenium, recognizing that missing doses can lead to a return of symptoms associated with fatigue and thyroid issues Read Review.
Additionally, a few users suggest combining Selenium with other supplements, such as Zinc or L-tyrosine, for enhanced effects in combating fatigue Read ReviewRead Review. Many users have noticed significant improvements in their overall energy levels, with reports indicating a surge of energy and a sense of rejuvenation after starting their Selenium regimen Read Review. As always, it is recommended to consult healthcare professionals before starting any new supplementation regimen, especially when dealing with chronic health conditions.
7.5
Significant energy boost
98 people found this helpful
I've been using the product for two weeks, and I've noticed a significant improvement in my energy levels. I would recommend this to anyone suffering from fatigue or general exhaustion. Life is long enough, and stress can be debilitating, affecting both physical and mental health.
9
Great overall health
4 people found this helpful
After two months of selenium, I feel fantastic. My skin glows, my mood has improved, and my fatigue has dissipated. I believe this is one of the best products for overall health maintenance, and the tablets are easy to swallow.
7.5
Increased energy levels
525 people found this helpful
I started taking Selenium to address issues like dull and brittle hair, gastrointestinal problems, fatigue, and to boost my immune system. My dermatologist suggested combining it with Zinc. The results were quite remarkable! I felt a surge of energy and woke up much more vigorously. In addition, my nails improved dramatically with rapid growth, and I experienced clearer skin. I highly recommend this supplement as its benefits are extensive; however, results may vary per individual.
7.5
Vital deficiency addressed
2 people found this helpful
A deficiency of selenium could present symptoms like muscle weakness, chronic fatigue, and weakened immunity. Living in an ecologically unfavourable area, I bought selenium upon my homeopath's advice. After a course, my condition improved significantly.
9
Fatigue reduction
I’ve noticed that the fatigue disappears after taking this supplement.
7.5
Improved energy levels
1 people found this helpful
Since taking the supplement, my energy levels and mental clarity have significantly improved. I feel alert and focused throughout the day, accomplishing more without the weariness. It's easy to take and has not caused any negative side effects.
9
Improved energy
1 people found this helpful
Since starting this supplement, my overall well-being has improved swiftly. The fatigue has decreased remarkably, especially when combined with L-tyrosine. Drowsiness and weakness have subsided, leaving me with energy and clarity. I truly appreciate this combination.
6
Reliable supplement
2 people found this helpful
I consistently purchase from this trustworthy brand, which offers excellent hermetic packaging and a convenient cap. I bought selenium for hair shedding, and it has numerous benefits. It has helped my immune system and reduced my fatigue, making it easier to combine with biotin.
9
Long-term use
This is the best antioxidant for me; I intend to take it for life. Taking one pill twice daily has made a noticeable difference. My fatigue has been considerably reduced.
7.5
Eye relief
1 people found this helpful
This supplement is fantastic for my thyroid eye disease. It has alleviated symptoms like fatigue and watering in my eyes. I’ve noticed improvement since taking these daily; missing doses makes symptoms return, indicating a possible selenium deficiency.
9
Fatigue relief
1 people found this helpful
Selenium has significantly helped me; my fatigue has vanished and my whole body feels rejuvenated. It turns out I was deficient in this vitamin. Thank you!
8
Selenium effects on chronic fatigue
Therapeutic Effect and Metabolic Mechanism of A Selenium-Polysaccharide from Green Tea on Chronic Fatigue Syndrome.
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
7
CoQ10 and selenium may benefit ME/CFS
Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
8
Selenium nanoparticles for chronic fatigue
Ultrasound-assisted preparation of sweet corn cob polysaccharide selenium nanoparticles alleviates symptoms of chronic fatigue syndrome.
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
References
Wang J, Wang X, Xiu W, Li C, Yu S, et al. Ultrasound-assisted preparation of sweet corn cob polysaccharide selenium nanoparticles alleviates symptoms of chronic fatigue syndrome. Food Funct. 2025;16:133. 10.1039/d4fo04195j
Castro-Marrero J, Domingo JC, Cordobilla B, Ferrer R, Giralt M, et al. Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?. Antioxid Redox Signal. 2022;36:729. 10.1089/ars.2022.0018
Shao C, Song J, Zhao S, Jiang H, Wang B, et al. Therapeutic Effect and Metabolic Mechanism of A Selenium-Polysaccharide from Green Tea on Chronic Fatigue Syndrome. Polymers (Basel). 2018;10. 10.3390/polym10111269